Tissue Specific Cells Obtainable from hADSCs

As depicted in picture below, adipose tissue derived stem cells or stem cells extracted from fat are multipoint and capable of differentiating into many other cells to regenerate/repair the damaged tissues.

Adipose tissue-derived stem cells can differentiate to bone, fat, cartilage, muscle types, endothelium, neurons, skin, and liver lineages under defined differentiation conditions

hADSCs manufactured at SBS are differentiated to adipocyte, osteocytes and chondrocytes to confirm that they are multipoint stem cells with potentials to differentiate to other cells. Samples of hADSCs differentiated at SBS are shown below:

Adipogenic Differentiation

Verification of the Multipotency of hADSCs, isolated and expanded at SBS.
A) Adipocytes 14 days after induction of differentiation, stained with Goat anti-mouse FABP4 and NL577-conjugated Donkey Anti-goat IgG (red) as secondary antibody. Nuclei were counterstained with DAPI (blue). B) Adipocytes 14 days after induction of differentiation, negative control stained without first antibody.
Osteogenic Differentiation
Verification of the Multipotency of hADSCs, isolated and expanded at SBS.
B) Osteocytes 14 days after induction of differentiation, stained with mouse anti-human Ostecalcin and Alexa 488 Donkey Anti-mouse IgG (green) as secondary antibody. Nuclei were counterstained with DAPI (blue). B) Adipocytes 14 days after induction of differentiation, negative control stained without first antibody.
Chondrogenic Differentiation
Verification of the Multipotency of hADSCs, isolated and expanded at SBS.
E) Cross-section of chondrocyte pellet 21 days after induction of differentiation, stained with goat anti-human Aggrecan and NL577-conjugated Donkey Anti-goat IgG (red) as secondary antibody. Nuclei were counterstained with DAPI (blue). F) Adipocytes 14 days after induction of differentiation, negative control stained without first antibody.
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