Most tissues and organ systems of the body have a resident pool of tissue-specific stem cells that are stimulated and mobilised in response to trauma or disease. However, in many cases either the quantity of mobilised stem cells is not sufficient or time to mobilisation is too long. As a result the endogenous stem cells fail to regenerate injured or diseased tissues.
Application of stem cells offers a remarkable tool in regenerative medicine and has potential in regeneration of damaged tissues. Transplantation of autologous stem cells constitute a remarkable supportive tool in regenerative medicine without rejection risk or immunogenic reactions.
hADSC and SVF may only be used as a transplant product within the framework of a valid marketing authorization or within the framework of controlled clinical studies.