hADSCs-The frontier of Future Medicine

Stem cells are at the core of regenerative medicine, a branch of medicine that deals with replacing or regenerating damaged human cells, tissues, or organs to restore their normal and healthy function. The characteristics of hADSCs allow them to replace or repair damaged cells, thereby restoring the function of damaged tissues and promoting tissue regeneration. Stem cell transplantation is applicable to the treatment of diseases and tissue injuries caused by cell deficiency and disorders of cell differentiation that may result from a lack of appropriate cells or impaired cellular function. Among many types of stem cells, adipose tissue-derived stem cells (hADSCs) are one of the most extensively researched. Currently, many clinical trials are underway to establish treatments for human diseases using hADSCs, including:

Antiaging

hADSCs or SVF derived from adipose tissue improves regenerative property of fat grafting and improves tridimensional architecture of the reticular dermis and microvascular bed. Furthermore, it has been demonstrated that ADSCs transplantation produce many useful growth factors ...

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Cardiovascular Diseases

Experimental results have exhibited significant improvements in cardiac function and angiogenesis after stem cell transplantation. While some clinical trials are assessing the clinical efficacy of this new treatment method ...

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Diseases of Digestive System

Anti-inflammatory and regenerative potentials of stem cells have been utilised in the treatment of digestive system diseases. Stem cell treatment has been shown effective in the treatment of liver failure and Chron’s disease. Injection of hADSCs has been shown beneficial in the closure of perianal fistula ...

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Diabetes

Stem cell transplantation has shown important role in the pancreatic repair and its functional improvement. Positive metabolic effects have been consistently demonstrated in the literature for MSCs transplantation as a treatment for diabetes ...

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Neurological Disorders

Stem cell therapy for neural diseases carries enormous promise. Experimental results confirm that stem cell transplantation reduces both acute cerebral inflammation and chronic brain degeneration, and promotes long-term functional recovery of the brain. Stem cell transplantation also attenuates neurological deficits ...

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Wound Healing

Adipose tissue derived stem cells represent a new therapy for dermal wound healing. These cells, after transplantation, are recruited into wounded Skin and contribute to wound repair by transdifferentiation into skin cells and participate in dermal wound healing in physiological and pathological conditions ...

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