Stem cells are at the core of regenerative medicine, a branch of medicine that deals with replacing or regenerating damaged human cells, tissues, or organs to restore their normal and healthy function. The characteristics of hADSCs allow them to replace or repair damaged cells, thereby restoring the function of damaged tissues and promoting tissue regeneration. Stem cell transplantation is applicable to the treatment of diseases and tissue injuries caused by cell deficiency and disorders of cell differentiation that may result from a lack of appropriate cells or impaired cellular function. Among many types of stem cells, adipose tissue-derived stem cells (hADSCs) are one of the most extensively researched.
They are transforming healthcare with their regenerative capabilities across various fields, especially in anti-aging, joint health, hair growth, immune system support, and tissue repair:
Anti-Aging: Stem cells are used in therapies to rejuvenate skin by promoting cell renewal and collagen production, reducing wrinkles, and improving elasticity. This regenerative approach helps slow down the signs of aging at the cellular level.
Articulation: Stem cell therapy is increasingly used for joint issues like arthritis. By regenerating cartilage and reducing inflammation, stem cells can improve mobility and relieve pain, providing a promising alternative to joint replacements.
Hair Growth: Stem cells can stimulate hair follicles, promoting natural hair growth. This approach targets hair loss at the root cause, making it a valuable option for those seeking to restore hair density and health.
Immune System: In autoimmune conditions, stem cells can modulate immune responses, potentially reducing the severity of symptoms and preventing immune attacks on healthy tissues. This immune regulation is a breakthrough in treating chronic inflammatory diseases.
Tissue Regenerative Medicine: Stem cells are at the core of regenerative medicine, as they can repair or replace damaged tissues in organs, muscles, and skin. This ability to regenerate tissues is revolutionizing recovery for injuries and conditions involving tissue damage, such as heart disease or spinal injuries.
Currently, many clinical trials are underway to establish treatments for human diseases using hADSCs, including:
hADSCs or SVF derived from adipose tissue improves regenerative property of fat grafting and improves tridimensional architecture of the reticular dermis and microvascular bed. Furthermore, it has been demonstrated that ADSCs transplantation produce many useful growth factors ...
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Beneficial effect of stem cell transplantation has been reported in the treatment of a number of joint conditions such as osteoarthritis, cartilage defects, ligament injuries and bone formation ...
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Experimental results have exhibited significant improvements in cardiac function and angiogenesis after stem cell transplantation. While some clinical trials are assessing the clinical efficacy of this new treatment method ...
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Anti-inflammatory and regenerative potentials of stem cells have been utilised in the treatment of digestive system diseases. Stem cell treatment has been shown effective in the treatment of liver failure and Chron’s disease. Injection of hADSCs has been shown beneficial in the closure of perianal fistula ...
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Stem cell transplantation has shown important role in the pancreatic repair and its functional improvement. Positive metabolic effects have been consistently demonstrated in the literature for MSCs transplantation as a treatment for diabetes ...
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Stem cell therapy for neural diseases carries enormous promise. Experimental results confirm that stem cell transplantation reduces both acute cerebral inflammation and chronic brain degeneration, and promotes long-term functional recovery of the brain. Stem cell transplantation also attenuates neurological deficits ...
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Adipose tissue derived stem cells represent a new therapy for dermal wound healing. These cells, after transplantation, are recruited into wounded Skin and contribute to wound repair by transdifferentiation into skin cells and participate in dermal wound healing in physiological and pathological conditions ...
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